Consecutive Sample Injection Analysis in Tube Radial Distribution Chromatography

Tube radial distribution chromatography based on the tube flow, or annular in an open-tubular capillary has been reported, where flow is created through phase-separation multiphase flow. We have proposed first-ever procedure for consecutive sample injection analysis using chromatography. In basic terms, a commercially available HPLC system could be used with injector (0.2 μL volume) and fused-silica (250 cm long) as separation column instead of normal packed one, while built-in detection cell was replaced by improved on-capillary detection. A ternary mixed solution water/acetonitrile/ethyl acetate (3:8:4 volume ratio) delivered into eluent at rate 2.0 min−1. Model solutions 1-naphthol 2,6-naphthalenedisulfonic acid were consecutively analyzed present processing 6 samples per hour. Simple rapid performed because washing initialization no longer necessary. The obtained results provide clues to developing new methodologies which combine features both (separation) method (consecutive analysis).